With all injections, there is a risk of infection, bleeding, temporary increase in pain and injury to the structures along the course of the needle. Through sterile equipment and technique, we minimize the risk of infection. The risk of bleeding is minimized by discontinuation of blood thinners (this typically require approval from prescribing doctor) and non-steroidal anti-inflammatories (except Celebrex). By using X-ray guidance (fluoroscopy) we minimize risk of tissue injury to structures along the course of the needle. Nerve irritation is minimized by the use of local anesthetic to provide temporary relief that typically wears off after 3-6 hours. The steroid medication can take 3-5 days to take full effect, so patients may experience increased soreness for a couple days after the procedure. For radiofrequency ablation, there is a risk of nerve damage from lesioning other nerves; to minimize this risk, sensory and motor stimulation are performed to insure placement of the probe is along the medial branch and is not coming into contact with other nerves. If you have an active infection or are unable to stop blood thinners then you may not be a candidate for these types of injections.